MINPP1 Protein (AA 31-487) (His tag)

Produktnummer ABIN4370405

Produktdetails

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 31-487

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses MINPP1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 (C-6His)

Sequenz: SLLEPRDPVA SSLSPYFGTK TRYEDVNPVL LSGPEAPWRD PELLEGTCTP VQLVALIRHG TRYPTVKQIR KLRQLHGLLQ ARGSRDGGAS STGSRDLGAA LADWPLWYAD WMDGQLVEKG RQDMRQLALR LASLFPALFS RENYGRLRLI TSSKHRCMDS SAAFLQGLWQ HYHPGLPPPD VADMEFGPPT VNDKLMRFFD HCEKFLTEVE KNATALYHVE AFKTGPEMQN ILKKVAATLQ VPVNDLNADL IQVAFFTCSF DLAIKGVKSP WCDVFDIDDA KVLEYLNDLK QYWKRGYGYT INSRSSCTLF QDIFQHLDKA VEQKQRSQPI SSPVILQFGH AETLLPLLSL MGYFKDKEPL TAYNYKKQMH RKFRSGLIVP YASNLIFVLY HCENAKTPKE QFRVQMLLNE KVLPLAYSQE TVSFYEDLKN HYKDILQSCQ TSEECELARA NSTSDELVDH HHHHH

Produktmerkmale: Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 produced by transfected human cellss is a secreted protein with sequence (Ser31-Leu487) of Human MINPP1 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 7.5.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Andere Bezeichnung: mipp (MINPP1 Produkte)

Synonyme: HIPER1 Protein, MINPP2 Protein, MIPP Protein, AA408516 Protein, minpp1 Protein, zgc:56080 Protein, zgc:76991 Protein, zgc:153026 Protein, multiple inositol-polyphosphate phosphatase 1 Protein, multiple inositol polyphosphate histidine phosphatase 1 Protein, multiple inositol-polyphosphate phosphatase 1b Protein, multiple inositol-polyphosphate phosphatase 1a Protein, MINPP1 Protein, Minpp1 Protein, minpp1b Protein, minpp1a Protein

Sub Type: Fusionprotein

Hintergrund: Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
Alternative Names: Multiple Inositol Polyphosphate Phosphatase 1, 2,3-Bisphosphoglycerate 3-Phosphatase, 2,3-BPG Phosphatase, Inositol (1,3,4,5)-Tetrakisphosphate 3-Phosphatase, Ins(1,3,4,5)P(4) 3-Phosphatase, MINPP1, MIPP

Molekulargewicht: 53.14 kDa

UniProt: Q9UNW1