KYNU Protein (His tag)
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- Target Alle KYNU Proteine anzeigen
- KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Maus
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Quelle
- Baculovirus infected Insect Cells
- Aufreinigungstag / Konjugat
- Dieses KYNU Protein ist gelabelt mit His tag.
- Verwendungszweck
- Recombinant Mouse KYNU/Kynureninase Protein (His Tag)(Active)
- Sequenz
- Met 1-Ser 464
- Produktmerkmale
- A DNA sequence encoding the mouse KYNU (Q9CXF0) (Met 1-Ser 464) was expressed,with a C-terminal polyhistidine tag.
- Reinheit
- > 94 % as determined by SDS-PAGE
- Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to oxidize 3-hydroxykynurenine.The specific activity is > 100 pmoles/min/μg.
- Top Product
- Discover our top product KYNU Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0
- Lagerung
- 4 °C,-20 °C,-80 °C
- Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- KYNU (Kynureninase (L-Kynurenine Hydrolase) (KYNU))
- Andere Bezeichnung
- KYNU/Kynureninase (KYNU Produkte)
- Hintergrund
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Background: Genetic studies in mouse and human suggest that kynureninase activity may influence blood pressure and renal function. The gene coding kynureninase (KYNU) is also located on chromosome band 2q14-q23, where a linkage peak for essential hypertension was previously detected in the Chinese Han population.The results show that the rare KYNU variant Arg188Gln affects kynureninase activity and are consistent with the hypothesis that this mutation can predispose to essential hypertension.
Synonym: 4432411A05Rik
- Molekulargewicht
- 53.7 kDa
- UniProt
- Q9CXF0
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