Kallikrein 8 Protein (KLK8) (His tag)

Produktnummer ABIN7318700

Dieses Recombinant Kallikrein 8-Protein wird in Human Cells exprimiert.

Kurzübersicht für Kallikrein 8 Protein (KLK8) (His tag) (ABIN7318700)

Target: Kallikrein 8 (KLK8)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Kallikrein 8 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human KLK-8/Kallikrein-8 Protein (His Tag)

Sequenz: Gln29-GLy260

Produktmerkmale: Recombinant Human Kallikrein 8 is produced by our Mammalian expression system and the target gene encoding Gln29-GLy260 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Kallikrein 8 (KLK8)

Andere Bezeichnung: KLK-8/Kallikrein-8

Hintergrund:

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.

Synonym: Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine Protease 19, Serine Protease TADG-14, Tumor-Associated Differentially Expressed Gene 14 Protein, KLK8, NRPN, PRSS19, TADG14

Molekulargewicht: 26.0 kDa

UniProt: O60259

Pathways: Komplementsystem