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Kallikrein 1 Protein (KLK1) (His tag)

Recombinant Kallikrein 1-Protein exprimiert in Human Cells.
Produktnummer ABIN7320811

Kurzübersicht für Kallikrein 1 Protein (KLK1) (His tag) (ABIN7320811)

Target

Alle Kallikrein 1 (KLK1) Proteine anzeigen
Kallikrein 1 (KLK1)

Protein-Typ

Recombinant

Spezies

  • 12
  • 4
  • 3
  • 1
  • 1
Maus

Quelle

  • 9
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human Cells

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses Kallikrein 1 Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Mouse Kallikrein 1/KLK1 Protein (His Tag)

    Sequenz

    Pro19-Asp261

    Produktmerkmale

    Recombinant Mouse Kallikrein-1 is produced by our Mammalian expression system and the target gene encoding Pro19-Asp261 is expressed with a 6His tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 7.5.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target

    Kallikrein 1 (KLK1)

    Andere Bezeichnung

    Kallikrein 1/KLK1

    Hintergrund

    Background: Kallikreins belongs to the family of trypsin-like serine proteases, many of which are associated with a variety of cancers. Kallikrein 1 (KLK1) is also known as tissue kallikrein and urinary kallikrein. KLK1 is synthesized as a 261 amino acid (aa) protein that contains a 18 aa signal peptide and a 241 aa proprotein. An important physiological function of KLK1 cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Kinins regulate vasodilation, blood pressure reduction, smooth muscle relaxation and contraction, pain induction and inflammation.

    Synonym: Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6, mGK-6

    Molekulargewicht

    27.9 kDa

    UniProt

    P15947

    Pathways

    Komplementsystem
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