Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

IDE Protein (His tag)

Dieses Recombinant IDE-Protein wird in Human Cells produziert.
Produktnummer ABIN7318623

Kurzübersicht für IDE Protein (His tag) (ABIN7318623)

Target

Alle IDE Proteine anzeigen
IDE (Insulin-Degrading Enzyme (IDE))

Protein-Typ

Recombinant

Spezies

  • 12
  • 4
  • 2
Human

Quelle

  • 7
  • 4
  • 2
  • 2
  • 1
  • 1
Human Cells

Reinheit

> 95 % as determined by reducing SDS-PAGE.
  • Aufreinigungstag / Konjugat

    Dieses IDE Protein ist gelabelt mit His tag.

    Verwendungszweck

    Recombinant Human IDE/Insulysin Protein (His Tag)

    Sequenz

    Met42-Leu1019

    Produktmerkmale

    Recombinant Human Insulin-Degrading Enzyme is produced by our Mammalian expression system and the target gene encoding Met42-Leu1019 is expressed with a 6His tag at the C-terminus.

    Endotoxin-Niveau

    < 1.0 EU per μg as determined by the LAL method.
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!
    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 12.620,45 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 20.480,57 €

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,0.05 % Brij35,10 %Glycerol, pH 7.5.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target

    IDE (Insulin-Degrading Enzyme (IDE))

    Andere Bezeichnung

    IDE/Insulysin

    Hintergrund

    Background: Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.

    Synonym: Insulin-Degrading Enzyme, Abeta-Degrading Protease, Insulin Protease, Insulinase, Insulysin, IDE

    Molekulargewicht

    114.3 kDa

    UniProt

    P14735

    Pathways

    SARS-CoV-2 Protein Interaktom
Sie sind hier:
Chat with us!