IDE Protein (His tag)
Kurzübersicht für IDE Protein (His tag) (ABIN7318623)
Target
Alle IDE Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses IDE Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human IDE/Insulysin Protein (His Tag)
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Sequenz
- Met42-Leu1019
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Produktmerkmale
- Recombinant Human Insulin-Degrading Enzyme is produced by our Mammalian expression system and the target gene encoding Met42-Leu1019 is expressed with a 6His tag at the C-terminus.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!ProduktExpressionssystemKonjugatOriginPreis abExpressionssystem HEK-293 CellsKonjugat His tagOrigin HumanPreis ab 12.620,45 €Expressionssystem Cell-free protein synthesis (CFPS)Konjugat Strep TagOrigin HumanPreis ab 20.480,57 €Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
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Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)
custom-made IDE Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (His tag)custom-made IDE Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Insulin-Degrading Enzyme (IDE) (AA 920-1019) protein (GST tag)IDE Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) (AA 1-1019) protein (GST tag)IDE Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Degrading Enzyme (IDE) protein (Myc-DYKDDDDK Tag)IDE Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,0.05 % Brij35,10 %Glycerol, pH 7.5.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- IDE (Insulin-Degrading Enzyme (IDE))
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Andere Bezeichnung
- IDE/Insulysin
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Hintergrund
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Background: Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.
Synonym: Insulin-Degrading Enzyme, Abeta-Degrading Protease, Insulin Protease, Insulinase, Insulysin, IDE
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Molekulargewicht
- 114.3 kDa
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UniProt
- P14735
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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