IgG2a Fc (AA 98-322) Protein

Produktnummer ABIN7321258

Recombinant IgG2a Fc-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für IgG2a Fc (AA 98-322) Protein (ABIN7321258)

Target: IgG2a Fc

Protein-Typ: Recombinant

Spezies: Ratte

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 98-322

Verwendungszweck: Recombinant Rat IgG2A Fc/Igg-2a Protein

Sequenz: Val98-Lys322

Produktmerkmale: Recombinant Rat Immunoglobulin G2A Fc is produced by our Mammalian expression system and the target gene encoding Val98-Lys322 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, pH 8.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: IgG2a Fc

Andere Bezeichnung: IgG2A Fc/Igg-2a

Hintergrund: Ig gamma-2A chain C region,Igg-2a,Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains-two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78 % amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

Molekulargewicht:

Calculated MW: 35.2 kDa

Observed MW: 30-35 kDa

UniProt: P20760