HK3 Protein (His-GST)
Kurzübersicht für HK3 Protein (His-GST) (ABIN7196087)
Target
Alle HK3 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses HK3 Protein ist gelabelt mit His-GST.
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Verwendungszweck
- Recombinant Human Hexokinase-3/HK3 Protein (His & GST Tag)
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Sequenz
- Met 1-Val 923
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Produktmerkmale
- A DNA sequence encoding the human HK3 (P52790) (Met 1-Val 923) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Hexokinase 3 (White Cell) (HK3) (AA 1-923) protein (GST tag)
HK3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Hexokinase 3 (White Cell) (HK3) (AA 1-61) protein (His-IF2DI Tag)HK3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Hexokinase 3 (White Cell) (HK3) protein (Myc-DYKDDDDK Tag)HK3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as sterile solution of 50 mM Tris, 100 mM NaCl, pH 7.4
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- HK3 (Hexokinase 3 (White Cell) (HK3))
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Andere Bezeichnung
- Hexokinase-3/HK3
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Hintergrund
- HKIII,HXK3,Hexokinase-3, also known as Hexokinase type III, HKIII and HK3, is a protein which belongs to thehexokinase family. Hexokinase-3 / HK3 is anenzymewhich in humans is encoded by theHK2gene. Hexokinases phosphorylate glucoseto produceglucose 6-phosphate, committing glucose to theglycolytic pathway. In mammalian tissues hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, with the exception of hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, thisallostericenzyme is inhibited by its product glucose 6-phosphate.
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Molekulargewicht
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Calculated MW: 127 kDa
Observed MW: 115 kDa
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Gen-ID
- 3101
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UniProt
- P52790
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Pathways
- Carbohydrate Homeostasis, Warburg Effekt
Target
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