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GNMT Protein (His tag)

GNMT Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318543
  • Target Alle GNMT Proteine anzeigen
    GNMT (Glycine N-Methyltransferase (GNMT))
    Protein-Typ
    Recombinant
    Spezies
    • 10
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses GNMT Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human GNMT Protein (His Tag)
    Sequenz
    Met 1-Asg294
    Produktmerkmale
    Recombinant Human Glycine N-Methyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Asg294 is expressed with a 6His tag at the N-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product GNMT Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    GNMT (Glycine N-Methyltransferase (GNMT))
    Andere Bezeichnung
    GNMT (GNMT Produkte)
    Synonyme
    glycine N-methyltransferase Protein, CpipJ_CPIJ015956 Protein, Gnmt Protein, GNMT Protein
    Hintergrund

    Background: Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.

    Synonym: Glycine N-Methyltransferase, GNMT

    Molekulargewicht
    34.9 kDa
    UniProt
    Q14749
    Pathways
    Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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