Glutathione Synthetase Protein (GSS) (His tag)

Produktnummer ABIN7318542

Dieses Recombinant Glutathione Synthetase-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Glutathione Synthetase Protein (GSS) (His tag) (ABIN7318542)

Target: Glutathione Synthetase (GSS)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Glutathione Synthetase Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human GSS Protein (His Tag)

Sequenz: Ala2-Val474

Produktmerkmale: Recombinant Human Glutathione Synthetase is produced by our E.coli expression system and the target gene encoding Ala2-Val474 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, pH 7.5 .

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Glutathione Synthetase (GSS)

Andere Bezeichnung: GSS

Hintergrund:

Background: Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.

Synonym: Glutathione Synthetase, GSH Synthetase, GSH-S, Glutathione Synthase, GSS

Molekulargewicht: 53.5 kDa

UniProt: P48637

Pathways: Warburg Effekt