Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DCUN1D1 Protein (His tag)

DCUN1D1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7318395
  • Target Alle DCUN1D1 Proteine anzeigen
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 2
    Human
    Quelle
    • 3
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses DCUN1D1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human DCUN1D1 Protein (His Tag)
    Sequenz
    Met 1-Val259
    Produktmerkmale
    Recombinant Human DCN1-Like Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Val259 is expressed with a 6His tag at the N-terminus.
    Reinheit
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product DCUN1D1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
    Andere Bezeichnung
    DCUN1D1 (DCUN1D1 Produkte)
    Hintergrund

    Background: DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.

    Synonym: DCN1-Like Protein 1, DCUN1 Domain-Containing Protein 1, Defective in Cullin Neddylation Protein 1-Like Protein 1, Squamous Cell Carcinoma-Related Oncogene, DCUN1D1, DCUN1L1, RP42, SCCRO

    Molekulargewicht
    32.3 kDa
    UniProt
    Q96GG9
Sie sind hier:
Kundenservice