LAP3 Protein (His tag)
Kurzübersicht für LAP3 Protein (His tag) (ABIN7317187)
Target
Alle LAP3 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses LAP3 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human LAP3/Cytosol Aminopeptidase Protein (His Tag)
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Sequenz
- Met 1-Ala519
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Produktmerkmale
- A DNA sequence encoding the human LAP3 (NP_056991.2) (Met1-Ala519) was expressed with a polyhistidine tag at the C-terminus.
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
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Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20 % glycerol, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Haltbarkeit
- 12 months
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- LAP3 (Cytosol Aminopeptidase (LAP3))
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Andere Bezeichnung
- LAP3/Cytosol Aminopeptidase
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Hintergrund
- HEL-S-106,LAP,LAPEP,PEPS,LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine residues. It catalyzes the removal of unsubstituted N-terminal amino acids from various peptides and is presumably involved in the processing and regular turnover of intracellular proteins. Leucine aminopeptidases are involved in many pathological disorders and regulate cell proliferation, invasion, and/or angiogenesis of tumors. A recent study showed that LAP3 is highly expressed in several malignant and affects tumor angiogenesis. LAP3 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with LAP3 include Bacterial Vaginosis and Trichomoniasis.
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Molekulargewicht
- 57.6 kDa
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Gen-ID
- 51056
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NCBI Accession
- NP_056991
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UniProt
- P28838
Target
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