CTH Protein
Kurzübersicht für CTH Protein (ABIN7318370)
Target
Alle CTH Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Human Cystathionine γ-Lyase/CTH Protein
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Sequenz
- Met 1-Ser405
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Produktmerkmale
- Recombinant Human Cystathionine Gamma-Lyase is produced by our E.coli expression system and the target gene encoding Met1-Ser405 is expressed.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
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Andere Bezeichnung
- Cystathionine gamma-Lyase/CTH
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Hintergrund
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Background: Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.
Synonym: Cystathionine Gamma-Lyase, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase, CTH
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Molekulargewicht
- 44.7 kDa
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UniProt
- P32929
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Pathways
- ER-Nucleus Signaling, Warburg Effekt
Target
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