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CD70 Protein (mFc Tag)

CD70 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319773
  • Target Alle CD70 Proteine anzeigen
    CD70 (CD70 Molecule (CD70))
    Protein-Typ
    Recombinant
    Spezies
    • 34
    • 10
    • 1
    • 1
    • 1
    Human
    Quelle
    • 26
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses CD70 Protein ist gelabelt mit mFc Tag.
    Verwendungszweck
    Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)
    Sequenz
    Gln45-Pro193
    Produktmerkmale
    Recombinant Human CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln45-Pro193 is expressed with a mFc tag at the C-terminus.
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD70 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CD70 (CD70 Molecule (CD70))
    Andere Bezeichnung
    CD27 Ligand/TNFSF7/CD70 (CD70 Produkte)
    Synonyme
    CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
    Hintergrund

    Background: CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64 % aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

    Synonym: CD70 antigen, CD70, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27LG, TNFSF7, CD27L

    Molekulargewicht
    43 kDa
    UniProt
    P32970
    Pathways
    Cancer Immune Checkpoints
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