CD70 Protein (AA 47-195) (His tag)

Produktnummer ABIN7320908

Dieses Recombinant CD70-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD70 Protein (AA 47-195) (His tag) (ABIN7320908)

Target: CD70 (CD70 Molecule (CD70))

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 47-195

Aufreinigungstag / Konjugat: Dieses CD70 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Mouse CD27 Ligand/TNFSF7/CD70 (N-10His)

Sequenz: Gln47-Pro195

Produktmerkmale: Recombinant Mouse CD27 Ligand/CD70 is produced by our Mammalian expression system and the target gene encoding Gln47-Pro195 is expressed with a 10His tag at the N-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD27 Ligand/TNFSF7/CD70

Hintergrund: CD27 ligand,CD27L,CD27LG,CD70,CD70 antigen,TNFSF7,Tumor necrosis factor ligand superfamily member 7,CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64 % aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Molekulargewicht:

Calculated MW: 19.0 kDa

Observed MW: 25-30 kDa

UniProt: Q05A52

Pathways: Cancer Immune Checkpoints