CD59 Protein (CD59) (AA 26-102) (His tag)

Produktnummer ABIN7319910

Dieses Recombinant CD59-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CD59 Protein (CD59) (AA 26-102) (His tag) (ABIN7319910)

Target: CD59

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 26-102

Aufreinigungstag / Konjugat: Dieses CD59 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CD59 (C-6His)

Sequenz: Leu26-Asn102

Produktmerkmale: Recombinant Human CD59 Glycoprotein is produced by our Mammalian expression system and the target gene encoding Leu26-Asn102 is expressed with a 6His tag at the C-terminus.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: CD59

Andere Bezeichnung: CD59

Hintergrund: 16.3A5,1F5,1F5 antigen,20 kDa homologous restriction factor,CD59,CD59 antigen,CD59 glycoprotein,EL32,FLJ38134,FLJ92039,G344,HRF-20,HRF20,MAC-IP,MACIF,MIC11,MIC11MSK21,MIN1,MIN2,MIN3,MIRL,p18-20,CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

Molekulargewicht:

Calculated MW: 9.8 kDa

Observed MW: 15-20 kDa

Gen-ID: 966

UniProt: P13987

Pathways: Komplementsystem