CD59 Protein (CD59) (His tag)
Kurzübersicht für CD59 Protein (CD59) (His tag) (ABIN7319910)
Target
Alle CD59 Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Aufreinigungstag / Konjugat
- Dieses CD59 Protein ist gelabelt mit His tag.
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Verwendungszweck
- Recombinant Human CD59 (C-6His)
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Sequenz
- Leu26-Asn102
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Produktmerkmale
- Recombinant Human CD59 Glycoprotein is produced by our Mammalian expression system and the target gene encoding Leu26-Asn102 is expressed with a 6His tag at the C-terminus.
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Endotoxin-Niveau
- < 1.0 EU per μg as determined by the LAL method.
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CD59 (CD59) (AA 26-102) protein (Fc Tag)
CD59 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD59 (CD59) (AA 1-128) protein (GST tag)CD59 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Please refer to the printed manual for detailed information.
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Buffer
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD59
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Andere Bezeichnung
- CD59
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Hintergrund
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Background: CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Synonym: 1F5 antigen, 1F5, 20 kDa homologous restriction factor, CD59 antigen, CD59 glycoprotein, CD59, HRF20, HRF-20, MACIF, MAC-IP, MIC11, MIC11MSK21, MIN1, MIN2, MIN3, MIRL, p18-20, 16.3A5, EL32, FLJ38134, FLJ92039, G344
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Molekulargewicht
- 9.8 kDa
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UniProt
- P13987
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Pathways
- Komplementsystem
Target
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