Cathepsin Z Protein (CTSZ) (His tag)

Produktnummer ABIN7319393

Dieses Recombinant Cathepsin Z-Protein wird in Human Cells produziert.

Kurzübersicht für Cathepsin Z Protein (CTSZ) (His tag) (ABIN7319393)

Target: Cathepsin Z (CTSZ)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Cathepsin Z Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cathepsin Z Protein (His Tag)

Sequenz: Gly24-Val303

Produktmerkmale: Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Cathepsin Z (CTSZ)

Andere Bezeichnung: Cathepsin Z

Hintergrund:

Background: Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.

Synonym: Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ

Molekulargewicht: 32.5 kDa

UniProt: Q9UBR2

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones