Cardiotrophin 1 Protein (CTF1) (His tag)

Produktnummer ABIN7318248

Recombinant Cardiotrophin 1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für Cardiotrophin 1 Protein (CTF1) (His tag) (ABIN7318248)

Target: Cardiotrophin 1 (CTF1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Cardiotrophin 1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Cardiotrophin-1/CTF1 Protein (His Tag)

Sequenz: Met 1-Ala201

Produktmerkmale: Recombinant Human Cardiotrophin-1 is produced by our E.coli expression system and the target gene encoding Met1-Ala201 is expressed with a 6His tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Lagerung: -20 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Antigendetails

Target: Cardiotrophin 1 (CTF1)

Andere Bezeichnung: Cardiotrophin-1/CTF1

Hintergrund:

Background: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.

Synonym: Cardiotrophin-1, CT-1, CTF1,

Molekulargewicht: 22.6 kDa

UniProt: Q16619

Pathways: JAK-STAT Signalweg