BMP2 Protein (AA 283-396) (His tag)

Produktnummer ABIN7321264

Dieses Recombinant BMP2-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für BMP2 Protein (AA 283-396) (His tag) (ABIN7321264)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human, Ratte, Maus

Quelle: Escherichia coli (E. coli)

Applikation: Cell Culture (CC)

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 283-396

Aufreinigungstag / Konjugat: Dieses BMP2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human/Mouse/Rat BMP-2 Protein

Sequenz: Gln283-Arg396

Produktmerkmale: Recombinant Human/Mouse/Rat Bone Morphogenetic Protein 2 is produced by our E.coli expression system and the target gene encoding Gln283-Arg396 is expressed.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: < 0.1 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is <1.0 μg/mL.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 12 months

Antigendetails

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Andere Bezeichnung: BMP-2

Hintergrund: BMP-2,BMP-2A,BMP2,BMP2A,Bone Morphogenetic Protein 2,Bone Morphogenetic Protein 2A,Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

Molekulargewicht:

Calculated MW: 13.8 kDa

Observed MW: 14 kDa

Gen-ID: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation