Angiopoietin 1 Protein (ANGPT1) (Fc Tag)

Produktnummer ABIN7319856

Dieses Recombinant Angiopoietin 1-Protein wird in Human Cells exprimiert.

Kurzübersicht für Angiopoietin 1 Protein (ANGPT1) (Fc Tag) (ABIN7319856)

Target: Angiopoietin 1 (ANGPT1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: >95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Angiopoietin 1 Protein ist gelabelt mit Fc Tag.

Verwendungszweck: Recombinant Human Angiopoietin-1/ANG1 (N-Fc)

Sequenz: Asp256-Phe498

Produktmerkmale: Recombinant Human Angiopoietin-1 is produced by our Mammalian expression system and the target gene encoding Asp256-Phe498 is expressed with a Fc tag at the N-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: Angiopoietin-1/ANG1

Hintergrund:

Background: Angiopoietin-1 (Ang-1) is a secreted glycoprotein that plays a critical role in the development and maintenance of the vascular system. The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. Angiopoietin-1 can protect against pulmonary arterial hypertension, reduce the extent of fibrosis and remodeling in infarcted diabetic myocardium, and enhance tumor progression and metastasis.

Synonym: AGP1, AGPT, Ang1, ANG-1, angiopoietin 1, Angiopoietin-1, ANGPT1

Molekulargewicht: 53.9 kDa

UniProt: Q15389

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process