CD79b Protein (PE,His tag)

Produktnummer ABIN7125887

Recombinant CD79b-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für CD79b Protein (PE,His tag) (ABIN7125887)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD79b Protein ist gelabelt mit PE,His tag.

Verwendungszweck: PE-Labeled Human CD79B Protein, His Tag (Site-specific conjugation)

Sequenz: Ala 29 - Asp 159

Produktmerkmale: PE-Labeled Human CD79B, His Tag is produced via site-specific conjugation of PE to Human CD79B, His Tag under optimal conditions with a proprietary technology. Human CD79B, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 29 - Asp 159 (Accession # P40259-1).

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.8 kDa.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, 0.5 % BSA, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C, aviod light

Antigendetails

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Andere Bezeichnung: CD79B

Hintergrund: Synonyms: CD79b,B29,IGB,Ig-beta,
B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

Molekulargewicht: 18.8 kDa

NCBI Accession: NP_000617

Pathways: BCR Signaling