CD226 Protein (CD226) (His tag)

Produktnummer ABIN7121305

Recombinant CD226-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für CD226 Protein (CD226) (His tag) (ABIN7121305)

Target: CD226

Protein-Typ: Recombinant

Spezies: Hund

Quelle: HEK-293 Cells

Reinheit: >95 % as determined by SDS-PAGE.

Güteklasse: SPR verified

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD226 Protein ist gelabelt mit His tag.

Verwendungszweck: Canine DNAM-1 / CD226 Protein, His Tag (SPR verified)

Sequenz: Glu 32 - Gln 263

Produktmerkmale: Canine DNAM-1, His Tag (DN1-C52H4) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Gln 263 (Accession # E2R115-1).

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.2 kDa. The protein migrates as 36-50 kDa under reducing (R) condition due to glycosylation.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Antigendetails

Target: CD226

Andere Bezeichnung: DNAM-1 / CD226

Hintergrund: Synonyms: DNAM1,CD226,PTA1,
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

Molekulargewicht: 28.2 kDa

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints