CD5 Protein (CD5) (PE,His tag)

Produktnummer ABIN7121288

Dieses Recombinant CD5-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für CD5 Protein (CD5) (PE,His tag) (ABIN7121288)

Target: CD5

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Produktdetails

Aufreinigungstag / Konjugat: Dieses CD5 Protein ist gelabelt mit PE,His tag.

Verwendungszweck: PE-Labeled Human CD5 Protein, His Tag (Site-specific conjugation)

Sequenz: Arg 25 - Pro 372

Produktmerkmale: PE-Labeled Human CD5, His Tag (CD5-HP2H6) is produced via site-specific conjugation of PE to Human CD5, His Tag under optimal conditions with a proprietary technology. Human CD5, His Tag is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Pro 372 (Accession # P06127-1).

Anwendungsinformationen

Applikationshinweise: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.2 kDa.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, 0.5 % BSA, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: -20°C, aviod light

Antigendetails

Target: CD5

Andere Bezeichnung: CD5

Hintergrund: Synonyms: CD5,LEU1,
Description: T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

Molekulargewicht: 42.2 kDa