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CD79b Protein (CD79b Molecule, Immunoglobulin-Associated beta) (AA 29-159) (His tag,AVI tag,Biotin)

CD79B Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN7013833
$1,675.38
Zzgl. Versandkosten $45.00
Lieferung in 5 Werktagen
  • Target Alle CD79b (CD79B) Proteine anzeigen
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 29-159
    Spezies
    • 14
    • 5
    • 2
    • 2
    • 2
    Human
    Quelle
    • 13
    • 4
    • 3
    • 3
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD79b Protein ist gelabelt mit His tag,AVI tag,Biotin.
    Verwendungszweck
    Biotinylated Human CD79B Protein, His,Avitag™ (MALS verified)
    Spezifität
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Kommentare

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, 0.2 M Arginine, pH 7.4
    Lagerung
    -20 °C
  • Target
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Andere Bezeichnung
    CD79B (CD79B Produkte)
    Synonyme
    B29, Ig-beta, Igb, Igbeta, AGM6, IGB, CD79B antigen, CD79b molecule, Cd79b, CD79B
    Hintergrund
    B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
    Molekulargewicht
    18.8 kDa
    NCBI Accession
    NP_000617
    Pathways
    BCR Signaling
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