Glucagon Receptor Protein (GCGR) (AA 26-136) (His tag)
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- Target Alle Glucagon Receptor (GCGR) Proteine anzeigen
- Glucagon Receptor (GCGR)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-136
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Glucagon Receptor Protein ist gelabelt mit His tag.
- Produktmerkmale
- Human GCGR / Glucagon receptor Protein, His Tag (MALS verified)
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 0.1 EU per μg by the LAL method.
- Top Product
- Discover our top product GCGR Protein
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- Applikationshinweise
- MALS verified
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- Glucagon Receptor (GCGR)
- Andere Bezeichnung
- GCGR (GCGR Produkte)
- Hintergrund
- G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
- Molekulargewicht
- 14.9 kDa
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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