LGR5 Protein (AA 22-561) (His tag)
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- Target Alle LGR5 Proteine anzeigen
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-561
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses LGR5 Protein ist gelabelt mit His tag.
- Produktmerkmale
- Human LGR5 / GPR49 protein, His Tag
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LGR5 Protein
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Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-543) protein (Fc Tag)
LGR5 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) proteinLGR5 Spezies: Human Wirt: HEK-293 Cells Synthetic Nanodisc
Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-561) protein (His tag)LGR5 Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Lagerung
- -20 °C
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- Target
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- Andere Bezeichnung
- LGR5 (LGR5 Produkte)
- Hintergrund
- LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.
- Molekulargewicht
- 62.0 kDa
- NCBI Accession
- NP_003658
- Pathways
- WNT Signalweg
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