Topoisomerase II alpha Protein (AA 1354-1473)
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- Target Alle Topoisomerase II alpha (TOP2A) Proteine anzeigen
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1354-1473
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- AA 1354-1473
- Produktmerkmale
- Cynomolgus TRAIL R2 / DR5 / TNFRSF10B Protein, His Tag (MALS verified)
- Reinheit
- >90 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product TOP2A Protein
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Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1435-1531) protein (GST tag)
TOP2A Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1-1531) protein (Strep Tag)Crystallography grade TOP2A Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1-1528) protein (Strep Tag)Crystallography grade TOP2A Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 50 mM Tris, 0.5 M KCl, pH 8.0
- Lagerung
- -80 °C
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- Target
- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
- Andere Bezeichnung
- TOP2A (TOP2A Produkte)
- Synonyme
- TOP2 Protein, TP2A Protein, TOP2A Protein, Top-2 Protein, TOP-2 Protein, F12B17.110 Protein, F12B17_110 Protein, thimet metalloendopeptidase 2 Protein, fc08c07 Protein, wu:fc08c07 Protein, DNA topoisomerase II alpha Protein, DNA topoisomerase II, alpha isozyme Protein, topoisomerase (DNA) II alpha Protein, Zincin-like metalloproteases family protein Protein, TOP2A Protein, Bm1_08705 Protein, Top2a Protein, AT5G10540 Protein, top2a Protein
- Hintergrund
- DNA topoisomerase 2-alpha (TOP2A) is also known as DNA topoisomerase II, alpha isozyme and TOP2. It is a topoisomerase which control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation. Also it is the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations.
- Molekulargewicht
- 12.8 kDa
- NCBI Accession
- NP_001058
- Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
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