CD226 Protein (CD226) (AA 19-247) (mFc-His Tag)

Produktnummer ABIN6961117

Produktdetails

Target: CD226

Protein-Typ: Recombinant

Proteineigenschaft: AA 19-247

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD226 Protein ist gelabelt mit mFc-His Tag.

Applikation: ELISA

Verwendungszweck: Recombinant human DNAM-1 protein with C-terminal mouse Fc and 6xHis tag

Spezifität: DNAM-1 (Glu19-Asn247) mFc (Pro99-Lys330) 6xHis tag

Produktmerkmale: Extracellular Domain Protein

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Reinheit: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Antigendetails

Target: CD226

Andere Bezeichnung: DNAM-1 (CD226 Produkte)

Hintergrund: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Molekulargewicht: predicted molecular mass of 53.5 kDa after removal of the signal peptide.

Gen-ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints