Neurotrophin 4 Protein (NTF4)

Produktnummer ABIN6700310

Hersteller Produkt- Nr.: 009-001-w07-0010

Dieses Recombinant Neurotrophin 4-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für Neurotrophin 4 Protein (NTF4) (ABIN6700310)

Target: Neurotrophin 4 (NTF4)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: 97,00%

Produktdetails

Hersteller Produkt- Nr.: 009-001-w07-0010

Hersteller: Rockland

Verwendungszweck: Human Neurotrophin-4 Recombinant Protein

Aufreinigung: Neurotrophin-4 purity was determined to be greater than 97% as determined by HpLC, analysis by UV-Spectroscopy at 280nm, and by reducing and non-reducing SDS-pAGE.

Endotoxin-Niveau: Measured by LAL is typically ≤ 1 EU/μg protein.

Biological Activity Comment: Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6) ED50 ≤ 20 ng/mL (≥ 5.0 x 10^4 units/mg).

Anwendungsinformationen

Applikationshinweise:

Application Note: Neurotrophin-4 Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Neurotrophin-4 in immunological assays.

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 10 μL (10-100 μL)

Konzentration: 0.1 mg/mL

Buffer:

Buffer: 0.1 % Trifluoroacetic acid

Stabilizer: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

Haltbarkeit: 6 months

Antigendetails

Target: Neurotrophin 4 (NTF4)

Andere Bezeichnung: NTF4

Hintergrund:

Synonyms: Neurotrophin 5 (NT-5), Neurotrophic Factor 4

Background: Neurotrophin-4 (NT-4) is an important member of the nerve growth factor (NGF) family of proteins along with NT-3, BDNF and NGF. Neurotrophins act in a paracrine and/or autocine manner to control neuronal numbers and dendrite outgrowth. These functions are thought to be communicated by TrkB, a receptor tryrosine kinase that NT-4 shares with BDNF. Recombinant human NT-4 is a non-glycosylated, non-covalently linked homodimer, containing two 131 amino acid chains, with a total molecular weight of 28.1 kDa.

UniProt: P34130

Pathways: RTK Signalweg