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ATF3 Protein (AA 1-181)

ATF3 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN667497
  • Target Alle ATF3 Proteine anzeigen
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-181
    Spezies
    • 6
    • 3
    • 1
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    ATF3, 1-181aa, Human, E.coli
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ATF3 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol
    Lagerung
    4 °C
  • Target
    ATF3 (Activating Transcription Factor 3 (ATF3))
    Andere Bezeichnung
    ATF3 (ATF3 Produkte)
    Synonyme
    zgc:55526 Protein, ATF3 Protein, LRG-21 Protein, LRF-1 Protein, LRFI Protein, atf-3 Protein, activating transcription factor 3 Protein, activating transcription factor 3 L homeolog Protein, atf3 Protein, ATF3 Protein, Atf3 Protein, atf3.L Protein
    Hintergrund
    ATF3 (activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription, it is presumed, by sequestering inhibitory co-factors away from the promoter. Synonyms: Activating transcription factor 3, ATF3deltaZip2, ATF3deltaZip2c, ATF3deltaZip3, cAMP dependent transcription factor ATF3, Cyclic AMP dependent transcription factor ATF3, Cyclic AMP-dependent transcription factor ATF-3. NCBI no.: NP_001665
    Molekulargewicht
    20.6kDa (181aa)
    Pathways
    Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Unfolded Protein Response
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