GLRX3 Protein (AA 1-335) (His tag)

Produktnummer ABIN666992

Produktdetails

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-335

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses GLRX3 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Glutaredoxin-3, 1-335aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT

Lagerung: 4 °C

Antigendetails

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Andere Bezeichnung: Glutaredoxin-3 (GLRX3 Produkte)

Hintergrund: Glutaredoxin(GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ. Recombinant human Glutaredoxin-3, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Thioredoxin-like protein 2, GLRX3, PICOT, TXNL2, GRX3, glutaredoxin 4, bA500G10.4, GLRX4, GRX4, thioredoxin-like 2, thioredoxin-like 2, glutaredoxin 3,. NCBI no.: NP_006532

Molekulargewicht: 39.6kDa (355aa), confirmed by MALDI-TOF

Pathways: Cell RedoxHomeostasis