DLD Protein (AA 36-509) (His tag)
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- Target Alle DLD Proteine anzeigen
- DLD (Dihydrolipoamide Dehydrogenase (DLD))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 36-509
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses DLD Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- DLD, 36-509aa, Human, His tag, E.coli
- Reinheit
- > 95 % by SDS - PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1M NaCl, 10% glycerol
- Lagerung
- 4 °C
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- Target
- DLD (Dihydrolipoamide Dehydrogenase (DLD))
- Andere Bezeichnung
- DLD (DLD Produkte)
- Hintergrund
- DLD (Dihydrolipoamide dehydrogenase), also known as GCSL (glycine cleavage system L protein), is a component of the glycine cleavage system as well as of the alpha ketoacid dehydrogenase complexes. DLD is a flavin-dependent oxidoreductase and functions as a component of the alpha-keto acid dehydrogenase, the pyruvate dehydrogenase, the alpha-ketoglutarate dehydrogenase, the branched-chain alpha-keto acid dehydrogenase and as the L protein in the mitochondrial glycine cleavage system. Mutations in DLD protein can result in MSUD (maple syrup urine disease) and congenital infantile lactic acidosis. Recombinant human DLD protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DLDH, E3, GCSL, LAD, PHE3, Dihydrolipoyl dehydrogenase, mitochondrial Diaphorase, Dihydrolipoamide dehydrogenase, Dihydrolipoyl dehydrogenase, Dihydrolipoyl dehydrogenase mitochondrial, DLD, E3 component of pyruvate dehydrogenase, E3 component of pyruvate dehydrogenase complex 2 oxo glutarate complex branched chain keto acid dehydrogenase complex, Glycine cleavage system L protein, Glycine cleavage system protein L, Lipoamide reductase, Lipoyl dehydrogenase, PHE 3,. NCBI no.: NP_000099
- Molekulargewicht
- 54.4 kDa (511aa)
- Pathways
- Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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