STIM1 Protein (AA 23-213) (CaM)

Produktnummer ABIN666653

Produktdetails

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 23-213

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses STIM1 Protein ist gelabelt mit CaM.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: STIM1, 23-213aa, Human, CaM tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5

Lagerung: 4 °C

Antigendetails

Target: STIM1 (Stromal Interaction Molecule 1 (STIM1))

Andere Bezeichnung: STIM1 (STIM1 Produkte)

Hintergrund: Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated Ca(2+) entry, a process of extracellular Ca(2+) influx in response to the depletion of Ca(2+) stores in the endoplasmic reticulum (ER). STIM1 localizes predominantly to the ER, upon Ca(2+) release from the ER, STIM1 translocates to the ER-plasma membrane junctions and activates Ca(2+) channels. Recombinant Calmodulin tagged STIM was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: GOK, D11S4896E, Stromal interaction molecule 1, STIM1, Stromal interaction molecule 1 D11S4896E, SIM, STIM 1, Stim1 stromal interaction molecule 1. NCBI no.: NP_003147

Molekulargewicht: 38 kDa (343 aa), confirmed by MALDI-TOF.

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling