Prolactin Receptor Protein (PRLR) (AA 25-234) (Fc Tag)
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- Target Alle Prolactin Receptor (PRLR) Proteine anzeigen
- Prolactin Receptor (PRLR)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 25-234
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Prolactin Receptor Protein ist gelabelt mit Fc Tag.
- Sequenz
- AA 25-234
- Produktmerkmale
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.0 kDa. The protein migrates as 64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Reinheit
- >95 % as determined by SDS-PAGE.
- Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PRLR Protein
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Prolactin Receptor (PRLR) (AA 25-234) protein (His tag)
PRLR Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-236) protein (His tag)PRLR Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 20-229) protein (His tag)PRLR Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-235) protein (Fc Tag)PRLR Spezies: Hund Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Prolactin Receptor (PRLR) (AA 25-234) (Active) protein (His tag)PRLR Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Prolactin Receptor (PRLR) protein (Fc Tag)PRLR Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Prolactin Receptor (PRLR) (AA 1-622) protein (GST tag)PRLR Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Prolactin Receptor (PRLR) (AA 25-234) protein (Fc Tag)PRLR Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prolactin Receptor (PRLR) protein (His tag,Fc Tag)PRLR Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Prolactin Receptor (PRLR) protein (His tag)PRLR Spezies: Ratte Wirt: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handhabung
- Please avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
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- Target
- Prolactin Receptor (PRLR)
- Andere Bezeichnung
- Prolactin R (PRLR Produkte)
- Hintergrund
- As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.
- Molekulargewicht
- 51.0 kDa
- NCBI Accession
- NP_000940
- Pathways
- JAK-STAT Signalweg, Response to Growth Hormone Stimulus
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