Galectin 3 Protein (LGALS3) (Soluble)
Kurzübersicht für Galectin 3 Protein (LGALS3) (Soluble) (ABIN624591)
Target
Alle Galectin 3 (LGALS3) Proteine anzeigenProtein-Typ
Spezies
Wirt
Reinheit
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Proteineigenschaft
- Soluble
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Spezifität
- Galectin-3 (Gal-3) is a member of the galectin family of beta-galactoside-binding proteins, which is involved in both intracellular and extracellular functions and exhibits anti-apoptotic properties. Gal-3 is implicated in many biological processes, including cell differentiation, growth, adhesion, angiogenesis and inflammation, and is expressed in a wide range of neoplasms. Gal-3 acts as a regulator of tumor metastasis, and several studies have shown a correlation between levels of Gal-3 and tumor progression in liver, thyroid, colon, gastric and breast carcinomas, making Gal-3 an emerging cancer marker. Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
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Produktmerkmale
- Recombinant Human Galectin-3
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Aufreinigung
- Purified
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Endotoxin-Niveau
- < 1 EU/ug
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute with 0.5 ml distilled water
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Konzentration
- Total protein concentration 0.1 mg/ml after reconstitution
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Buffer
- Phosphate buffered saline
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Lagerung
- 4 °C
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- Galectin 3 (LGALS3)
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Andere Bezeichnung
- Galectin-3
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Substanzklasse
- Chemical
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Hintergrund
- Synonyms: MAC2 Purified recombinant galectin-3 expressed in E.coli.
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Molekulargewicht
- 26.0kD (250 amino acid residues)
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Pathways
- RTK Signalweg
Target
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