Complement C3b Protein

Produktnummer ABIN622147

Native Complement C3b-Protein exprimiert in Human.

Kurzübersicht für Complement C3b Protein (ABIN622147)

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Protein-Typ: Native

Spezies: Human

Quelle: Human

Reinheit: > 90 %. By SDS-PAGE

Produktdetails

Produktmerkmale: Native Human C3b

Aufreinigung: Purified C3b from human serum

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/ml

Buffer: Phosphate buffered saline, pH 7.2

Lagerung: -20 °C

Antigendetails

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Andere Bezeichnung: C3b

Hintergrund: Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.

Molekulargewicht: 180 kDa

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling