Complement C3b Protein
C3b
Spezies: Human
Wirt: Human
Native
> 90 %. By SDS-PAGE
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- Target Alle Complement C3b (C3b) Produkte
- Complement C3b (C3b) (Complement C3 beta Chain (C3b))
- Protein-Typ
- Native
- Spezies
- Human
- Quelle
- Human
- Produktmerkmale
- Native Human C3b
- Aufreinigung
- Purified C3b from human serum
- Reinheit
- > 90 %. By SDS-PAGE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/ml
- Buffer
- Phosphate buffered saline, pH 7.2
- Lagerung
- -20 °C
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- Target
- Complement C3b (C3b) (Complement C3 beta Chain (C3b))
- Andere Bezeichnung
- C3b (C3b Produkte)
- Hintergrund
- Cleavage of the C3-alpha chain at peptide bond 77 results in production of C3a and C3b fragments. The C3b fragment is a glycoprotein composed of the modified C3-alpha chain and the intact C3-beta chain. Nascent C3b has the transient ability to form a covalent ester bond with a variety of target surfaces. Once bound to target surfaces C3b becomes an essential subunit of both the classical and alternative pathway C5 cleaving enzymes.
- Molekulargewicht
- 180 kDa
- Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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