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GM-CSF Protein

CSF2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Produktnummer ABIN935389
  • Target Alle GM-CSF (CSF2) Proteine anzeigen
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 31
    • 13
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 35
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequenz
    MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
    Produktmerkmale
    Purified recombinant Human GM-CSF protein
    Expression System: E.coli
    Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7 units/mg.
    Reinheit
    > 98 % pure
    Endotoxin-Niveau
    < 0.1 ng per μg (1 EU/μg).
    Top Product
    Discover our top product CSF2 Protein
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Kommentare

    Biological activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is approx. 0.05 ng/mL, corresponding to a specific activity of approx. 2 x 10^7 units/mg.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with distilled water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    Lyophilized from 10 mM HoAc.
    Handhabung
    Avoid repeated freeze/thaw cycles.
    Lagerung
    RT/-20 °C
  • Target
    GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
    Andere Bezeichnung
    GM-CSF (CSF2 Produkte)
    Hintergrund
    GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.
    Alternative Names: CSF-2 protein, MGI-1GM protein, Granulocyte/Macrophage Colony-Stimulating Factor protein, pluripoietin-alpha protein, GM-CSF protein
    Molekulargewicht
    14.2 kDa
    Pathways
    JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin
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