GM-CSF Protein
Kurzübersicht für GM-CSF Protein (ABIN5775831)
Target
Alle GM-CSF (CSF2) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Sequenz
- MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
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Produktmerkmale
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Purified recombinant Human GM-CSF protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is ? 0.05 ng/mL, corresponding to a specific activity of ? 2 x 10^7 units/mg. -
Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg).
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Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (Active) protein (His tag)
CSF2 Spezies: Maus Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (Active) proteinCSF2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-141) (Active) proteinCSF2 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-144) protein (Fc Tag)CSF2 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) protein (His tag)CSF2 Spezies: Ratte Wirt: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 1-144) protein (GST tag)CSF2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-141) (Active) protein (His tag)CSF2 Spezies: Maus Wirt: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) (AA 18-144) (Active) protein (His tag)CSF2 Spezies: Human Wirt: HEK-293 Cells > 95 % AcA, CC Active
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Kommentare
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Biological activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is approx. 0.05 ng/mL, corresponding to a specific activity of approx. 2 x 10^7 units/mg.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute with distilled water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM HoAc.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- RT/-20 °C
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- GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))
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Andere Bezeichnung
- GM-CSF
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Hintergrund
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GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.
Alternative Names: CSF-2 protein, MGI-1GM protein, Granulocyte/Macrophage Colony-Stimulating Factor protein, pluripoietin-alpha protein, GM-CSF protein -
Molekulargewicht
- 14.2 kDa
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Pathways
- JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin
Target
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