P4HTM Protein (AA 82-563) (His-SUMO Tag)
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- Target Alle P4HTM Proteine anzeigen
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 82-563
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses P4HTM Protein ist gelabelt mit His-SUMO Tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- VHYSNGDESS DPGPQHRAQG PGPEPTLGPL TRLEGIKVGH ERKVQLVTDR DHFIRTLSLK PLLFEIPGFL TDEECRLIIH LAQMKGLQRS QILPTEEYEE AMSTMQVSQL DLFRLLDQNR DGHLQLREVL AQTRLGNGWW MTPESIQEMY AAIKADPDGD GVLSLQEFSN MDLRDFHKYM RSHKAESSEL VRNSHHTWLY QGEGAHHIMR AIRQRVLRLT RLSPEIVELS EPLQVVRYGE GGHYHAHVDS GPVYPETICS HTKLVANESV PFETSCRQVS PNWGLPSILR PGTPMTQAQP CTVGVPLGMG PGDHWVIPVS PWEHPQLGTC SVPPLPYSYM TVLFYLNNVT GGGETVFPVA DNRTYDEMSL IQDDVDLRDT RRHCDKGNLR VKPQQGTAVF WYNYLPDGQG WVGDVDDYSL HGGCLVTRGT KWIANNWINV DPSRARQALF QQEMARLARE GGTDSQPEWA LDRAYRDARV EL
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product P4HTM Protein
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Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-502) protein (His tag)
custom-made P4HTM Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-503) protein (His tag)custom-made P4HTM Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM) (AA 1-563) protein (GST tag)P4HTM Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
- Andere Bezeichnung
- P4HTM (P4HTM Produkte)
- Hintergrund
- Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
- Molekulargewicht
- 70.51 kDa
- UniProt
- Q9NXG6
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