PRNP Protein (AA 29-231) (His tag)
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- Target Alle PRNP Proteine anzeigen
- PRNP (Prion Protein (PRNP))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 29-231
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Spezies
- Ratte
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses PRNP Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- GGWNTGGSRY PGQGSPGGNR YPPQSGGTWG QPHGGGWGQP HGGGWGQPHG GGWGQPHGGG WSQGGGTHNQ WNKPSKPKTN LKHVAGAAAA GAVVGGLGGY MLGSAMSRPM LHFGNDWEDR YYRENMYRYP NQVYYRPVDQ YSNQNNFVHD CVNITIKQHT VTTTTKGENF TETDVKMMER VVEQMCVTQY QKESQAYYDG RRS
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product PRNP Protein
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Prion Protein (PRNP) (AA 23-230) protein (Fc Tag)
PRNP Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Prion Protein (PRNP) (AA 23-230) protein (Fc Tag)PRNP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Prion Protein (PRNP) (AA 1-253) protein (GST tag)PRNP Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Prion Protein (PRNP) (AA 90-230) protein (Fc Tag)PRNP Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prion Protein (PRNP) (AA 23-229) protein (Fc Tag)PRNP Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Prion Protein (PRNP) (AA 1-73) protein (Fc Tag)custom-made PRNP Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Prion Protein (PRNP) proteinPRNP Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % ELISA, SDS, WB, IP
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PRNP (Prion Protein (PRNP))
- Andere Bezeichnung
- PRIO (PRNP Produkte)
- Hintergrund
- May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains .
- Molekulargewicht
- 26.34 kDa
- UniProt
- P13852
- Pathways
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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