CD276 Protein (CD276) (partial) (Fc Tag)

Produktnummer ABIN5608363

Dieses Recombinant CD276-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD276 Protein (CD276) (partial) (Fc Tag) (ABIN5608363)

Target: CD276

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Western Blotting (WB)

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: partial

Aufreinigungstag / Konjugat: Dieses CD276 Protein ist gelabelt mit Fc Tag.

Sequenz: Leu 29 - Pro 245

Endotoxin-Niveau: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Antigendetails

Target: CD276

Andere Bezeichnung: B7-H3

Hintergrund: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

Molekulargewicht: 50 kDa

Gen-ID: 80381

Pathways: Cancer Immune Checkpoints