Betacellulin Protein (BTC) (partial) (Fc Tag)
Kurzübersicht für Betacellulin Protein (BTC) (partial) (Fc Tag) (ABIN5608199)
Target
Alle Betacellulin (BTC) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- partial
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Aufreinigungstag / Konjugat
- Dieses Betacellulin Protein ist gelabelt mit Fc Tag.
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Sequenz
- Asp 32 - Tyr 111
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Endotoxin-Niveau
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Betacellulin (BTC) (AA 32-111) protein (His tag)
BTC Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (Fc Tag)BTC Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Applikationshinweise
- This recombinant protein can be used for WB.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Betacellulin (BTC)
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Andere Bezeichnung
- Betacellulin
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Hintergrund
- Probetacellulin can be cleaved into the Betacellulin (BTC) that is a single-pass type I membrane protein containing 1 EGF-like domain. Predominantly expressed in pancreas and small intestine,Betacellulin (BTC) is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. As a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells, Betacellulin (BTC) is also the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Betacellulin (BTC) was originally identified as a growth-promoting factor in mouse pancreatic beta-cell carcinoma cell line and has since been identified in humans. The amino acid sequence of mature mBTC is 82.5 % , identical with that of human BTC (hBTC), and both exhibit significant overall similarity with other members of the EGF family.
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Molekulargewicht
- 36.5 kDa
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Gen-ID
- 685
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UniProt
- P35070
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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