IL-9 Protein

Produktnummer ABIN5505705

Dieses Recombinant IL-9-Protein wird in Insektenzellen produziert.

Kurzübersicht für IL-9 Protein (ABIN5505705)

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Insektenzellen

Applikation: Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)

Reinheit: > 90 % , as determined by Coomassie stained SDS-PAGE.

Produktdetails

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human Interleukin-9 / IL9 protein expressed in Insect cells.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Endotoxin-Niveau: Less than 0.1 EU per μg of protein as determine by the LAL method

Biological Activity Comment: The ED50 is 0.1-0.5 ng/mL

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: > 50 μg/mL

Buffer: 1 x PBS, pH 7.4

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IL-9 (IL9) (Interleukin 9 (IL9))

Andere Bezeichnung: Interleukin-9 / IL9

Hintergrund: The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

Molekulargewicht: 14 kDa

NCBI Accession: NP_000581

Pathways: JAK-STAT Signalweg