Deoxyguanosine Kinase Protein (DGUOK) (His tag)

Produktnummer ABIN5505615

Dieses Recombinant Deoxyguanosine Kinase-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Deoxyguanosine Kinase Protein (DGUOK) (His tag) (ABIN5505615)

Target: Deoxyguanosine Kinase (DGUOK)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses Deoxyguanosine Kinase Protein ist gelabelt mit His tag.

Produktmerkmale:

• Recombinant human Purified recombinant protein of Human deoxyguanosine kinase (DGUOK), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E.coli, 50 μg (full length, N-term HIS tag, transcript variant 2) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Aufreinigung: Purified

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Deoxyguanosine Kinase (DGUOK)

Andere Bezeichnung: deoxyguanosine kinase

Hintergrund: In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.

Molekulargewicht: 17.3 kDa

NCBI Accession: NP_550440

Pathways: Ribonucleoside Biosynthetic Process