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Indian Hedgehog Protein (IHH)

IHH Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >96 % as determined by SDS-PAGE and HPLC. Func Active
Produktnummer ABIN2830462
  • Target Alle Indian Hedgehog (IHH) Proteine anzeigen
    Indian Hedgehog (IHH)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Spezies
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 14
    • 9
    • 2
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func)
    Sequenz
    IIGPGRVVGS RRRPPRKLVP LAYKQFSPNV PEKTLGASGR YEGKIARSSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDRLNSLAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRNKYGLL ARLAVEAGFD WVYYESKAHV HCSVKSEHSA AAKTGG
    Produktmerkmale
    Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce alkaline phosphatase production by C3H10T1/2(CCL-226) cells is 3.0-10 μg/mL.
    Reinheit
    >96 % as determined by SDS-PAGE and HPLC.
    Sterilität
    0.2 μm filtered
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  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    20 mM PB, pH 7.4, 150 mM NaCl
    Lagerung
    -20 °C
  • Target
    Indian Hedgehog (IHH)
    Andere Bezeichnung
    IHH (IHH Produkte)
    Hintergrund
    Relevance: Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity). {ECO:0000250}.
    Synonyms: IHH,
    Molekulargewicht
    19.8 kDa
    UniProt
    Q14623
    Pathways
    Hedgehog Signalweg
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