Thrombopoietin Protein (THPO) (Transcript Variant 1)

Produktnummer ABIN2733599

Produktdetails

Target: Thrombopoietin (THPO)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human Thrombopoietin (transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: ED50 was determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handhabung: Resuspend the protein in the desired concentration in proper buffer

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Thrombopoietin (THPO)

Andere Bezeichnung: Thrombopoietin (THPO Produkte)

Synonyme: MGDF Protein, MKCSF Protein, ML Protein, MPLLG Protein, THCYT1 Protein, TPO Protein, Mgdf Protein, Ml Protein, Mpllg Protein, Tpo Protein, Tpo1 Protein, Tpo2 Protein, Tpo3 Protein, Tpo4 Protein, tpo Protein, LOC100231762 Protein, thrombopoietin Protein, THPO Protein, Thpo Protein, thpo Protein

Hintergrund: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. [UniProtKB/Swiss-Prot Function]

Molekulargewicht: 18.6 kDa

NCBI Accession: NP_000451

Pathways: JAK-STAT Signalweg, Hormone Activity