Stanniocalcin 1 Protein (STC1) (DYKDDDDK-His Tag)

Produktnummer ABIN2732755

Dieses Recombinant Stanniocalcin 1-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für Stanniocalcin 1 Protein (STC1) (DYKDDDDK-His Tag) (ABIN2732755)

Target: Stanniocalcin 1 (STC1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses Stanniocalcin 1 Protein ist gelabelt mit DYKDDDDK-His Tag.

Produktmerkmale:

• Recombinant human Stanniocalcin 1 / STC1 (C-term DDK/His tag) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Stanniocalcin 1 (STC1)

Andere Bezeichnung: Stanniocalcin 1,stc1

Hintergrund: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.

Molekulargewicht: 26 kDa

NCBI Accession: NP_003146

Pathways: Hormone Activity