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Stanniocalcin 1 Protein (STC1) (His tag)

STC1 Spezies: Human Wirt: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7319806
  • Target Alle Stanniocalcin 1 (STC1) Proteine anzeigen
    Stanniocalcin 1 (STC1)
    Protein-Typ
    Recombinant
    Spezies
    • 7
    • 4
    • 3
    • 1
    Human
    Quelle
    • 8
    • 2
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses Stanniocalcin 1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human Stanniocalcin 1/STC-1 (C-6His)
    Sequenz
    Thr18-Ala247
    Produktmerkmale
    Recombinant Human Stanniocalcin 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus.
    Reinheit
    >95 % as determined by reducing SDS-PAGE.
    Endotoxin-Niveau
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product STC1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Stanniocalcin 1 (STC1)
    Andere Bezeichnung
    Stanniocalcin 1/STC-1 (STC1 Produkte)
    Synonyme
    STC Protein, Stc Protein, stc1 Protein, MGC82280 Protein, STC1 Protein, zgc:153307 Protein, LOC777959 Protein, stanniocalcin 1 Protein, stanniocalcin 1 L homeolog Protein, stanniocalcin 1 S homeolog Protein, STC1 Protein, Stc1 Protein, stc1.L Protein, stc1.S Protein, stc1 Protein, LOC777959 Protein
    Hintergrund

    Background: Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation.

    Synonym: Stanniocalcin 1, stanniocalcin-1, STC1, STC-1, STCSTC-1

    Molekulargewicht
    26.9 kDa
    UniProt
    P52823
    Pathways
    Hormone Activity
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