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PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Dieses Recombinant PC-Protein wird in HEK-293 Cells produziert.
Produktnummer ABIN2730237

Kurzübersicht für PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2730237)

Target

Alle PC Proteine anzeigen
PC (Pyruvate Carboxylase (PC))

Protein-Typ

Recombinant

Spezies

  • 3
  • 2
Human

Quelle

  • 4
  • 1
HEK-293 Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Proteineigenschaft

    Transcript Variant 3

    Aufreinigungstag / Konjugat

    Dieses PC Protein ist gelabelt mit Myc-DYKDDDDK Tag.

    Produktmerkmale

    • Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    PC (Pyruvate Carboxylase (PC))

    Andere Bezeichnung

    Pyruvic Carboxylase (Pc)

    Hintergrund

    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

    Molekulargewicht

    127.3 kDa

    NCBI Accession

    NP_001035806
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