PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
Kurzübersicht für PC Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) (ABIN2730237)
Target
Alle PC Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- Transcript Variant 3
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Aufreinigungstag / Konjugat
- Dieses PC Protein ist gelabelt mit Myc-DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human Pyruvic carboxylase (PC) (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- PC (Pyruvate Carboxylase (PC))
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Andere Bezeichnung
- Pyruvic Carboxylase (Pc)
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Hintergrund
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
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Molekulargewicht
- 127.3 kDa
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NCBI Accession
- NP_001035806
Target
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