KAT2B Protein (DYKDDDDK Tag)

Produktnummer ABIN2728344

Dieses Recombinant KAT2B-Protein wird in Insect cells (Sf9) produziert.

Kurzübersicht für KAT2B Protein (DYKDDDDK Tag) (ABIN2728344)

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Insect cells (Sf9)

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses KAT2B Protein ist gelabelt mit DYKDDDDK Tag.

Produktmerkmale:

• Recombinant human PCAF / KAT2B (full length, C-term DDK tag) protein expressed in Sf9 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))

Andere Bezeichnung: Pcaf,kat2b

Hintergrund: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Molekulargewicht: 93 kDa

NCBI Accession: NP_003875

Pathways: p53 Signalweg, Regulation of Carbohydrate Metabolic Process